BDBM174936 US9096593, P-2019

SMILES Cc1cnc2[nH]cc(Cc3ccc(NCc4ccc(nc4)C(F)(F)F)nc3)c2c1

InChI Key InChIKey=DXDZIZAESKHCEH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174936   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174936(US9096593, P-2019)
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174936(US9096593, P-2019)
Affinity DataIC50: <5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent